EDUCATION IN THE MANAGEMENT OF BLEEDING

A practical, evidence-based guide for front-line physicians on how to Treat the Bleed

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Terminate the code

Once bleeding is under control, terminate MHP.

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  • Termination process and criteria must be clear to all team members
    • Terminate protocol when hemostasis is achieved and patient is stabilized or when patient dies
    • Call transfusion medicine laboratory to terminate protocol
  • Transfer care to the most appropriate team
    • Complete charting and reconcile transfused components
    • Update patient’s family
    • Consider transporting patient to a higher acuity hospital if more intensive care is needed and/or definitive interventions are needed
  • Return all blood components and blood containers/coolers remaining at bedside to transfusion medicine laboratory
    • Blood components can be transfused up to 4 hours post-issue
    • Blood components issued and outside of a validated temperature controlled environment (i.e., blood cooler or fridge) for more than 1 hour (not cumulative) cannot return to inventory and will be discarded by the transfusion medicine lab; to ensure no wastage, portering should be contacted as soon as MHP stands down
  • Team debriefing
    • What went well and what can be done better next time
    • Improves compassion fatigue and promotes resiliency, enables quality improvement
  • Multidisciplinary review for quality assurance
    • Mortality and morbidity rounds – focusing on facts rather than “blame”
    • Others: trauma care committee, transfusion committee

Quality metrics should be tracked over all activations of the MHP.

  • Based on audits of blood component utilization:
    • Common errors made:
      • Starting right away with RBCs, FP, platelets in bleeding patients on the ward (for example, most GI bleeds can start with 2-4 RBCs and do not require other components)
      • Ordering 4 doses of platelets when clinicians are thinking of 4 units of platelets; correct terminology is “1 adult dose” = 4 units of whole blood–derived platelets = 1 unit of apheresis platelets
      • Not moving towards goal-directed therapy and sticking to ratio-based therapy, or focusing only on giving large amounts of RBCs
      • Not checking and/or replacing fibrinogen
      • Not getting a group and screen and overusing group O RBCs and AB plasma
        • Getting a group and screen post-transfusion of group O RBCs is still useful for determining the patient’s blood group

Example Set of Quality Metrics

  • Proportion of patients receiving tranexamic acid within 1 h of protocol activation
  • Proportion of patients in whom RBC transfusion is initiated within 15 min of protocol activation
  • Proportion of patients (of those requiring transfer for definitive care) with initiation of call for transfer within 60 min of protocol activation
  • Proportion of patients achieving temperature ≥36°C at termination of the protocol
  • Proportion of patients with hemoglobin levels maintained between 60 and 110 g/L during protocol activation, excluding certain pediatric populations (e.g., neonates) that may require higher hemoglobin values
  • Proportion of patients transitioned to group-specific RBCs and plasma within 90 min of arrival/onset of hemorrhage
  • Proportion of patients with appropriate activation (≥6 RBC units in first 24 h, >40 mL/kg per 24 h of RBCs in pediatric patients) or before this level in patients dying due to hemorrhage within 24 h
  • Proportion of patients without any blood component wastage (including plasma that is thawed and not used within the 5-day limit on another patient)

Regular simulations increases team building and non-technical skills in trauma

  • Can range from a table-top exercise to high fidelity in situ simulations
  • Consider having video recordings of lab and clinical areas to raise awareness of roles within the MHP

References:

  1. Barleycorn D, Lee GA. How Effective Is Trauma Simulation as an Educational Process for Healthcare Providers Within the Trauma Networks? A Systematic Review. Int Emerg Nurse. 2018;40:37-45.
  2. Callum JL, Yeh CH, Petrosoniak A, et al. A Regional Massive Hemorrhage Protocol Developed Through a Modified Delphi Technique. CMAJ Open. 2019;7(3):e546-561.
  3. Rao S, Martin F. Guideline for Management of Massive Blood Loss in Trauma. Update in Anaesthesia. 2012;28(1):125-129.
  4. Schmidt M, Haglund K. Debrief in Emergency Departments to Improve Compassion Fatigue and Promote Resiliency. J Trauma Nurse. 2017;24(5):317-322.
  5. Spahn DR, Bouillon B, Cerny V, et al. The European Guideline on Management of Major Bleeding and Coagulopathy Following Trauma: Fifth Edition. Crit Care. 2019;23(1):98.
  6. Yazer MH, Spinella PC, Doyle L, et al. Transfusion of Uncrossmatched Group O Erythrocyte-containing Products Does Not Interfere With Most ABO Typings. Anesthesiology. 2020;132(3):525-534.
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A practical, evidence-based guide for front-line physicians on how to treat acquired bleeding